Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.58 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.58 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.58 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.58 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.58 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.58 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.58 |
| ▸ | AKT1 | P31749 | 5/20 | 0.54 |
| ▸ | AKT2 | P31751 | 3/20 | 0.54 |
| ▸ | AKT3 | Q9Y243 | 3/20 | 0.54 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.54 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.54 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | PRKCG | P05129 | 1/20 | 0.49 |
| ▸ | PRKCB | P05771 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.49 |
| ▸ | PRKCH | P24723 | 1/20 | 0.49 |
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10565193 | 1.00 | LPAR1 (0.58) | LPAR1LPAR3LPAR5LPAR6LPAR4 | |
| SCHEMBL10951926 | 1.00 | LPAR1 (0.58) | LPAR1LPAR3LPAR5LPAR6LPAR4 | |
| SCHEMBL10950039 | 1.00 | LPAR1 (0.58) | LPAR1LPAR3LPAR5LPAR6LPAR4 | |
| SCHEMBL10951304 | 1.00 | LPAR1 (0.58) | LPAR1LPAR3LPAR5LPAR6LPAR4 | |
| SCHEMBL10954412 | 1.00 | LPAR1 (0.58) | LPAR1LPAR3LPAR5LPAR6LPAR4 | |
| SCHEMBL10950559 | 1.00 | LPAR1 (0.58) | LPAR1LPAR3LPAR5LPAR6LPAR4 | |
| SCHEMBL10948714 | 0.93 | LPAR3 (0.63) | LPAR1LPAR3LPAR5LPAR6LPAR4 | |
| SCHEMBL10952137 | 0.93 | LPAR3 (0.63) | LPAR1LPAR3LPAR5LPAR6LPAR4 | |
| SCHEMBL10952127 | 0.93 | LPAR3 (0.63) | LPAR1LPAR3LPAR5LPAR6LPAR4 | |
| SCHEMBL10948486 | 0.93 | PLA2G2C (0.52) | LPAR1LPAR3LPAR5LPAR6LPAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562005-A | ANTITUMOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-12-31 | — | — | US | claimed |
| US-4562005-A | ANTITUMOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-12-31 | — | — | US | disclosed |