Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28257643 | 0.94 | KMT2A (0.41) | KMT2ATSHRGAACYP2C19MEN1 | |
| SCHEMBL10950113 | 0.77 | MEN1 (0.34) | KMT2ATSHRGAACYP2C19MEN1 | |
| SCHEMBL2155988 | 0.77 | KMT2A (0.44) | KMT2ATSHRGAACYP2C19FAAH | |
| SCHEMBL11637314 | 0.75 | KMT2A (0.47) | KMT2ATSHRGAACYP2C19FAAH | |
| SCHEMBL3463995 | 0.72 | TSHR (0.34) | KMT2ATSHRMEN1 | |
| SCHEMBL10950116 | 0.72 | STAT3 (0.36) | KMT2ATSHRGAACYP2C19CA1 | |
| SCHEMBL28230028 | 0.71 | MEN1 (0.38) | KMT2ATSHRGAACYP2C19MEN1 | |
| Benzene SCHEMBL28852658 | 0.70 | KMT2A (0.57) | KMT2ATSHRGAACYP2C19FAAH | |
| SCHEMBL354454 | 0.70 | KMT2A (0.57) | KMT2ATSHRGAACYP2C19FAAH | |
| SCHEMBL11229234 | 0.69 | MEN1 (0.34) | KMT2ATSHRMEN1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4537905-A | HIGH CURATIVE AND PROTECTIVE ACTIVITY | BAYER AKTIENGESELLSCHAFT (DE) | 1985-08-27 | — | — | US | disclosed |