Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.57 |
| ▸ | ACE | P12821 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ECE1 | P42892 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755806 | 0.85 | MME (0.62) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL10954449 | 0.84 | CYP1A2 (0.54) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL10954444 | 0.84 | CYP1A2 (0.54) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL8165601 | 0.78 | CYP1A2 (0.80) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL10956150 | 0.78 | CYP1A2 (0.80) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL11940451 | 0.77 | CYP3A4 (0.63) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL28484063 | 0.77 | CPA1 (0.70) | MMECYP1A2 | |
| SCHEMBL6469019 | 0.77 | CPA1 (0.70) | MMECYP1A2 | |
| SCHEMBL7635307 | 0.76 | SLC7A5 (0.53) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6162382 | 0.76 | SLC7A5 (0.53) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4513009-A | GLYCINE, ALANINE AND SERINE DERIVATIVES | SOCIETE CIVILE BIOPROJET (FR) | 1985-04-23 | — | — | US | disclosed |