Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.68 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.68 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.68 |
| ▸ | ALB | P02768 | 1/20 | 0.68 |
| ▸ | PPARG | P37231 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.59 |
| ▸ | APEX1 | P27695 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | APAF1 | O14727 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.59 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.59 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658284 | 0.93 | NR1I2 (0.79) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL29587230 | 0.93 | NR1I2 (0.79) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10791906 | 0.92 | NR1I2 (0.63) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10787970 | 0.92 | NR1I2 (0.65) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL9308616 | 0.88 | NR1I2 (0.86) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL9021736 | 0.88 | NR1I2 (0.86) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL9021729 | 0.88 | NR1I2 (0.86) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL9433140 | 0.88 | NR1I2 (0.86) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11005821 | 0.88 | MAPT (0.62) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11103505 | 0.88 | NR1I2 (0.61) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4550102-A | ANTIBIOTIC, BACTERICIDE | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 1985-10-29 | — | — | US | disclosed |
| EP-0074645-A2 | New cephem compounds, processes for their preparation and pharmaceutical antibacterial composition containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-03-23 | — | — | EP | disclosed |