⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1564064 | 0.73 | — | — | |
| SCHEMBL5308018 | 0.72 | — | — | |
| SCHEMBL2831242 | 0.69 | — | — | |
| SCHEMBL8185148 | 0.69 | — | — | |
| SCHEMBL11126614 | 0.69 | — | — | |
| SCHEMBL9224100 | 0.69 | — | — | |
| SCHEMBL8927719 | 0.69 | — | — | |
| SCHEMBL4763081 | 0.67 | — | — | |
| SCHEMBL11293039 | 0.67 | — | — | |
| SCHEMBL4763079 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112390722-A | Continuous flow process for amine alkylation reaction | 浙江瑞博制药有限公司 | 2021-02-23 | — | — | CN | claimed |
| CN-1145902-A | Preparation of carbazones compounds | SHANGHAI HUALIAN PHARMACEUTICA (CN) | 1997-03-26 | — | — | CN | claimed |
| JP-11228560-A | — | — | None | — | — | JP | disclosed |
| CN-111196837-B | Preparation method of polyprenone and polyprenone preparation | 皕达生物科技(上海)有限公司 | 2023-07-28 | — | — | CN | disclosed |
| US-20210107942-A1 | TISSUE PROTECTIVE PEPTIDES AND PEPTIDE ANALOGS FOR PREVENTING AND TREATING DISEASES AND DISORDERS ASSOCIATED WITH TISSUE DAMAGE | ARAIM PHARMACEUTICALS INC (US) | 2021-04-15 | — | — | US | disclosed |
| CN-112390722-A | Continuous flow process for amine alkylation reaction | 浙江瑞博制药有限公司 | 2021-02-23 | — | — | CN | disclosed |
| CN-112390722-A | Continuous flow process for amine alkylation reaction | 浙江瑞博制药有限公司 | 2021-02-23 | — | — | CN | disclosed |
| US-10864253-B2 | Tissue protective peptides for preventing and treating diseases and disorders associated with tissue damage | ARAIM PHARMACEUTICALS, INC. (US) | 2020-12-15 | — | — | US | disclosed |
| US-20200360476-A1 | TISSUE PROTECTIVE PEPTIDES AND PEPTIDE ANALOGS FOR PREVENTING AND TREATING DISEASES AND DISORDERS ASSOCIATED WITH TISSUE DAMAGE | ARAIM PHARMACEUTICALS, INC. | 2020-11-19 | — | — | US | disclosed |
| US-20190134156-A1 | TISSUE PROTECTIVE PEPTIDES FOR PREVENTING AND TREATING DISEASES AND DISORDERS ASSOCIATED WITH TISSUE DAMAGE | ARAIM PHARMACEUTICALS, INC. | 2019-05-09 | — | — | US | disclosed |
| EP-2155203-B1 | AZAINDAZOLE COMPOUNDS AND METHODS OF USE | CHEMOCENTRYX INC (US) | 2018-10-17 | — | — | EP | disclosed |
| WO-2001004345-A1 | METHOD OF DIFFERENTIATING BETWEEN BACTERIAL AND VIRAL INFECTIONS | NEAR PATIENT TECHNOLOGIES LTD (GB) | 2001-01-18 | — | — | WO | disclosed |
| JP-H11228560-A | PRODUCTION OF BETA-HYDROXY-GAMMA-BUTYROLACTONE COMPOUNDS AND BETA-(METH)ACRYLOYLOXY-GAMMA-BUTYROLACTONE COMPOUNDS | MITSUBISHI RAYON CO LTD | 1999-08-24 | — | — | JP | disclosed |
| US-5849783-A | Autobiotics and their use in eliminating nonself cells | CELL RESEARCH CORPORATION (US) | 1998-12-15 | — | — | US | disclosed |
| CN-1145902-A | Preparation of carbazones compounds | SHANGHAI HUALIAN PHARMACEUTICA (CN) | 1997-03-26 | — | — | CN | disclosed |
| EP-0537267-B1 | AUTOBIOTICS AND THEIR USE IN ELIMINATING NONSELF CELLS IN VIVO | CELL RES CORP (US) | 1994-09-28 | — | — | EP | disclosed |
| EP-0537267-A1 | AUTOBIOTICS AND THEIR USE IN ELIMINATING NONSELF CELLS IN VIVO. | CELL RES CORP (US) | 1993-04-21 | — | — | EP | disclosed |
| US-5147652-A | Alpha ketoaldehydes | CELL RESEARCH CORPORATION (US) | 1992-09-15 | — | — | US | disclosed |
| WO-1992000727-A1 | AUTOBIOTICS AND THEIR USE IN ELIMINATING NONSELF CELLS IN VIVO | CELL RESEARCH CORPORATION (US) | 1992-01-23 | — | — | WO | disclosed |
| US-4066650-A | ANTIBACTERIAL AGENTS, ANTIVIRAL AGENTS, ANTINEOPLASTIC AGENTS, RADIOSENSITIZERS | EGYUD LASZLO G | 1978-01-03 | — | — | US | disclosed |