Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 3/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | PTGFR | P43088 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10963804 | 1.00 | PTGIR (0.33) | PTGIRPTGER4PTGER2NR1I2ESR1 | |
| SCHEMBL11036709 | 0.89 | PTGIR (0.35) | PTGIRPTGER4PTGER2NR1I2ESR1 | |
| SCHEMBL11036711 | 0.89 | PTGIR (0.35) | PTGIRPTGER4PTGER2NR1I2ESR1 | |
| SCHEMBL11116650 | 0.89 | PTGIR (0.33) | PTGIR | |
| SCHEMBL11116665 | 0.89 | PTGIR (0.33) | PTGIR | |
| SCHEMBL11074266 | 0.89 | PTGIR (0.36) | PTGIRPTGER4PTGER2NR1I2ESR1 | |
| SCHEMBL9317572 | 0.89 | PTGIR (0.36) | PTGIRPTGER4PTGER2NR1I2ESR1 | |
| SCHEMBL9317574 | 0.89 | PTGIR (0.36) | PTGIRPTGER4PTGER2NR1I2ESR1 | |
| SCHEMBL11062651 | 0.89 | PTGIR (0.36) | PTGIRPTGER4PTGER2NR1I2ESR1 | |
| SCHEMBL10962913 | 0.89 | PTGIR (0.36) | PTGIRPTGER4PTGER2NR1I2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051284-B1 | NOVEL THIAPROSTAGLANDIN E1 DERIVATIVES, PROCESS FOR PRODUCTION THEREOF, AND PHARMACEUTICALS CONTAINING THESE COMPOUNDS | TEIJIN LIMITED (JP) | 1985-01-09 | — | — | EP | disclosed |