Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ANPEP | P15144 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10964500 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1HPGDSMN1; SMN2ANPEP | |
| SCHEMBL2669219 | 0.90 | KDM4E (0.62) | KDM4EALDH1A1HPGDSMN1; SMN2ANPEP | |
| SCHEMBL10364634 | 0.90 | KDM4E (0.62) | KDM4EALDH1A1HPGDSMN1; SMN2ANPEP | |
| SCHEMBL31161054 | 0.87 | KDM4E (0.69) | KDM4EALDH1A1HPGDSMN1; SMN2GAA | |
| SCHEMBL74870 | 0.83 | ANPEP (0.81) | ALDH1A1ANPEPCA12CA1CA2 | |
| SCHEMBL74871 | 0.83 | ANPEP (0.81) | ALDH1A1ANPEPCA12CA1CA2 | |
| SCHEMBL31160975 | 0.82 | KDM4E (1.00) | KDM4EALDH1A1HPGDSMN1; SMN2GAA | |
| SCHEMBL31160801 | 0.82 | KDM4E (1.00) | KDM4EALDH1A1HPGDSMN1; SMN2GAA | |
| SCHEMBL10363008 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1HPGDSMN1; SMN2ANPEP | |
| SCHEMBL10362881 | 0.81 | KDM4E (0.76) | KDM4EALDH1A1HPGDSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0147211-A2 | 4H-3,1-benzoxazin-4-ones and related compounds, pharmaceutical compositions containing them, and processes for their preparation | SYNTEX (U.S.A.) INC. (US) | 1985-07-03 | — | — | EP | disclosed |