Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | APLNR | P35414 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624862 | 0.84 | KMT2A (0.53) | MEN1KMT2AAPLNRHSD17B10ALDH1A1 | |
| SCHEMBL4674015 | 0.83 | MEN1 (0.59) | MEN1KMT2AAPLNRHSD17B10ALDH1A1 | |
| SCHEMBL6246865 | 0.83 | MEN1 (0.59) | MEN1KMT2AAPLNRHSD17B10ALDH1A1 | |
| SCHEMBL6624872 | 0.83 | HSD17B10 (0.54) | MEN1KMT2AAPLNRHSD17B10ALDH1A1 | |
| SCHEMBL267732 | 0.81 | CYP3A4 (0.62) | MEN1KMT2AAPLNRHSD17B10ALDH1A1 | |
| SCHEMBL30831943 | 0.81 | HSD17B10 (0.75) | MEN1KMT2AAPLNRHSD17B10ALDH1A1 | |
| SCHEMBL1097902 | 0.81 | HSD17B10 (0.75) | MEN1KMT2AAPLNRHSD17B10ALDH1A1 | |
| SCHEMBL29392677 | 0.81 | CYP3A4 (0.62) | MEN1KMT2AAPLNRHSD17B10ALDH1A1 | |
| SCHEMBL4362583 | 0.81 | MEN1 (0.64) | MEN1KMT2AAPLNRHSD17B10ALDH1A1 | |
| SCHEMBL4687391 | 0.80 | KMT2A (0.59) | MEN1KMT2AAPLNRHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |