SCHEMBL10965409

SCHEMBL10965409

O=C(O)c1ccc(Oc2ccccc2C(=O)c2ccccc2Oc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 5/20 0.62
CTNNB1 P35222 1/20 0.56
TTR P02766 2/20 0.51
LPAR1 Q92633 5/20 0.50
LPAR5 Q9H1C0 5/20 0.50
PARP15 Q460N3 1/20 0.50
PARP10 Q53GL7 1/20 0.50
POLB P06746 1/20 0.49
PKM P14618 1/20 0.49
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28331260 0.93 SRD5A2 (0.64) SRD5A2CTNNB1TTRPARP15PARP10
SCHEMBL920326 0.91 SRD5A2 (0.59) SRD5A2CTNNB1TTRLPAR1LPAR5
SCHEMBL466194 0.87 CTNNB1 (0.71) CTNNB1MEN1KMT2ASMN1; SMN2
SCHEMBL7706043 0.87 SRD5A2 (0.68) SRD5A2TTRLPAR1LPAR5PARP15
SCHEMBL10448654 0.86 SRD5A2 (0.62) SRD5A2CTNNB1PARP10POLBMEN1
SCHEMBL9419499 0.86 SRD5A2 (0.58) SRD5A2CTNNB1POLB
SCHEMBL8746846 0.85 CTNNB1 (0.65) SRD5A2CTNNB1TTRPARP10MEN1
SCHEMBL29575432 0.85 CTNNB1 (0.65) SRD5A2CTNNB1TTRPARP10MEN1
Hydrochloric Acid SCHEMBL8433836 0.85 SRD5A2 (0.66) SRD5A2TTRLPAR1LPAR5PARP15
Hydrochloric Acid SCHEMBL8433842 0.85 SRD5A2 (0.66) SRD5A2TTRLPAR1LPAR5PARP15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4547553-A CROSSLINKED SOLVENT RESISTANT THERMOPLASTIC RESIN THE BOEING COMPANY (US) 1985-10-15 US disclosed