Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054290 | 0.97 | CYP19A1 (0.46) | CYP19A1HTTCTNNB1ALDH1A1MEN1 | |
| SCHEMBL8672674 | 0.84 | CYP19A1 (0.59) | CYP19A1HTTALDH1A1MEN1MAPT | |
| SCHEMBL8519711 | 0.84 | CYP19A1 (0.59) | CYP19A1HTTALDH1A1MEN1MAPT | |
| SCHEMBL8670350 | 0.84 | CYP19A1 (0.59) | CYP19A1HTTALDH1A1MEN1MAPT | |
| SCHEMBL1919197 | 0.81 | HTT (0.65) | CYP19A1HTTALDH1A1MEN1MAPT | |
| SCHEMBL1697048 | 0.80 | MEN1 (0.41) | HTTALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL11579865 | 0.80 | HTT (0.68) | HTTALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL6696912 | 0.79 | HTT (0.67) | CYP19A1HTTALDH1A1MEN1MAPT | |
| SCHEMBL6691190 | 0.79 | HTT (0.67) | CYP19A1HTTALDH1A1MEN1MAPT | |
| SCHEMBL6690414 | 0.79 | HTT (0.67) | CYP19A1HTTALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057440-B1 | AMINOPYRIMIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND FUNGICIDAL, INSECTICIDAL AND ACARICIDAL COMPOSITIONS CONTAINING THEM | SANKYO COMPANY LIMITED (JP) | 1985-05-22 | — | — | EP | disclosed |
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |