SCHEMBL10966366

SCHEMBL10966366

OC(c1cccnc1)c1ccc(Cl)cc1Cl.c1ccc(-c2ccc(COCc3ccc(-c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
GAA P10253 1/20 0.41
IDO1 P14902 4/20 0.40
SUCNR1 Q9BXA5 2/20 0.40
KCNA5 P22460 2/20 0.40
NR1I2 O75469 2/20 0.38
PGR P06401 2/20 0.38
ADORA3 P0DMS8 2/20 0.38
ADRA2B P18089 2/20 0.38
CHRM3 P20309 2/20 0.38
CNR1 P21554 2/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
DRD3 P35462 2/20 0.38
OPRK1 P41145 2/20 0.38
MC3R P41968 2/20 0.38
PDE4D Q08499 2/20 0.38
KCNH2 Q12809 2/20 0.38
MLNR O43193 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10972244 0.92 PDCD1 (0.42) CYP17A1SMN1; SMN2GAAIDO1SUCNR1
SCHEMBL11132188 0.89 IDO1 (0.39) CYP17A1IDO1NR1I2PGRADORA3
SCHEMBL10965347 0.85 IDO1 (0.48) CYP17A1SMN1; SMN2GAAIDO1NR1I2
SCHEMBL10966359 0.84 IDO1 (0.47) CYP17A1SMN1; SMN2GAAIDO1SUCNR1
SCHEMBL10968614 0.83 CYP2C9 (0.42) CYP17A1SMN1; SMN2GAAIDO1KCNA5
SCHEMBL10967675 0.83 SMN1; SMN2 (0.64) CYP17A1SMN1; SMN2GAAKCNA5SLC6A2
SCHEMBL10967991 0.82 SMN1; SMN2 (0.53) CYP17A1SMN1; SMN2GAAIDO1KCNA5
SCHEMBL10971823 0.82 CYP17A1 (0.53) CYP17A1SMN1; SMN2SUCNR1KCNA5KCNH2
SCHEMBL11136578 0.81 MRGPRX4 (0.40) IDO1TDO2TACR1TBXA2RPTGER1
SCHEMBL11026298 0.80 CYP19A1 (0.43) GAAIDO1KCNA5SLC6A4KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0148826-A1 FUNGICIDAL, HERBICIDAL AND PLANT GROWTH REGULATING PYRIDYL-CONTAINING ETHERS CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1985-07-24 EP disclosed
WO-1985000289-A1 FUNGICIDAL, HERBICIDAL AND PLANT GROWTH REGULATING PYRIDYL-CONTAINING ETHERS CHEVRON RESEARCH COMPANY (US) 1985-01-31 WO disclosed
US-4407806-A PRE- AND POSTEMERGENCE HERBICIDES CHEVRON RESEARCH COMPANY (US) 1983-10-04 US disclosed