Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | FDPS | P14324 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15880501 | 0.76 | PRKCI (0.62) | PRKCICYP1A2POLBLMNASMN1; SMN2 | |
| SCHEMBL23015823 | 0.75 | PRKCI (0.61) | PRKCICYP1A2POLBLMNAALDH1A1 | |
| SCHEMBL26739697 | 0.74 | PRKCI (0.49) | PRKCICYP1A2POLBLMNACYP3A4 | |
| SCHEMBL27627388 | 0.73 | PRKCI (0.63) | PRKCICYP1A2POLBLMNACYP3A4 | |
| SCHEMBL23624134 | 0.73 | PRKCI (0.48) | PRKCICYP1A2POLBLMNACYP3A4 | |
| SCHEMBL14185014 | 0.72 | PRKCI (0.47) | PRKCICYP1A2POLBLMNACYP3A4 | |
| SCHEMBL21766418 | 0.70 | PRKCI (0.52) | PRKCICYP1A2POLBLMNASMN1; SMN2 | |
| SCHEMBL25433124 | 0.70 | PRKCI (0.56) | PRKCILMNA | |
| SCHEMBL22125117 | 0.69 | SMARCA2 (0.67) | PRKCIARMEN1MAPTKMT2A | |
| SCHEMBL25702347 | 0.69 | PRKCI (0.54) | PRKCISMN1; SMN2CYP3A4CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0069622-B1 | PROCESS FOR THE PREPARATION OF BETA-CYCLO-SUBSTITUTED ETHYL AMINES, AND PRODUCTS SO OBTAINED | SANOFI S.A. (FR) | 1985-09-18 | — | — | EP | disclosed |