Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | FDPS | P14324 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730595 | 0.96 | KDM4E (0.52) | KDM4EKMT2AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL10730556 | 0.96 | KDM4E (0.52) | KDM4EKMT2AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL10735785 | 0.94 | KDM4E (0.52) | KDM4EKMT2AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL10735789 | 0.94 | KDM4E (0.52) | KDM4EKMT2AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL10737882 | 0.90 | KDM4E (0.46) | KDM4EKMT2AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL10737877 | 0.90 | KDM4E (0.46) | KDM4EKMT2AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL10731376 | 0.88 | KDM4E (0.56) | KDM4EKMT2AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL10731382 | 0.88 | KDM4E (0.56) | KDM4EKMT2AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL10737420 | 0.85 | TRPV1 (0.56) | KDM4EKMT2AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL10737428 | 0.85 | TRPV1 (0.56) | KDM4EKMT2AALDH1A1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157420-A2 | Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1985-10-09 | — | — | EP | disclosed |