Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.67 |
| ▸ | BCR | P11274 | 2/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096260 | 0.88 | ABL1 (0.76) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL13211674 | 0.86 | ABL1 (0.74) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL22721784 | 0.86 | GSTP1 (0.70) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL12715050 | 0.85 | ABL1 (0.79) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL13211660 | 0.84 | ABL1 (0.84) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL16812115 | 0.82 | HDAC4 (0.71) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL10843928 | 0.81 | PTPN1 (0.58) | ABCB1HDAC4HDAC2HDAC8GSTP1 | |
| SCHEMBL11819228 | 0.81 | ABL1 (0.73) | ABL1ABCB1BCRHDAC4HDAC2 | |
| Hydrogen Sulfide SCHEMBL27457713 | 0.79 | ABL1 (0.70) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL14524439 | 0.78 | ABL1 (0.62) | ABL1ABCB1BCRHDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068880-B1 | PHOTOGRAPHIC ELEMENTS CAPABLE OF PROVIDING OXOINDOLIZINE AND OXOINDOLIZINIUM DYE COMPOUNDS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-08-07 | — | — | EP | claimed |