Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4422929 | 0.92 | — | — | |
| Benzene SCHEMBL151182 | 0.78 | TSHR (0.59) | TDP1ALDH1A1TSHRTP53SMN1; SMN2 | |
| Benzene SCHEMBL25302841 | 0.74 | TSHR (0.54) | TDP1ALDH1A1TSHRTP53SMN1; SMN2 | |
| SCHEMBL1582872 | 0.72 | TDP1 (1.00) | TDP1ALDH1A1TSHRTP53SMN1; SMN2 | |
| SCHEMBL31220 | 0.72 | TDP1 (1.00) | TDP1ALDH1A1TSHRTP53SMN1; SMN2 | |
| SCHEMBL17028904 | 0.72 | TDP1 (1.00) | TDP1ALDH1A1TSHRTP53SMN1; SMN2 | |
| SCHEMBL1583161 | 0.72 | TDP1 (1.00) | TDP1ALDH1A1TSHRTP53SMN1; SMN2 | |
| SCHEMBL21178023 | 0.70 | TDP1 (0.96) | TDP1ALDH1A1TSHRTP53SMN1; SMN2 | |
| Iodide SCHEMBL9053819 | 0.70 | TDP1 (0.96) | TDP1ALDH1A1TSHRTP53SMN1; SMN2 | |
| Methane SCHEMBL28968045 | 0.70 | TDP1 (0.96) | TDP1ALDH1A1TSHRTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0062324-B1 | PERFLUOROGLYCIDYL ETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-01-09 | — | — | EP | disclosed |
| US-4384128-A | Perfluoroglycidyl ethers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-05-17 | — | — | US | disclosed |
| US-4360645-A | Perfluoroglycidyl ethers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-11-23 | — | — | US | disclosed |
| EP-0062324-A1 | Perfluoroglycidyl ethers | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-10-13 | — | — | EP | disclosed |