Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10731581 | 1.00 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL10566643 | 0.87 | PDE4B (0.51) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL10566644 | 0.87 | PDE4B (0.51) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL9834662 | 0.86 | PDE4B (0.52) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL9834667 | 0.86 | PDE4B (0.52) | PDE4APDE4BPDE4CPDE4DTSHR | |
| Hydrochloric Acid SCHEMBL10569610 | 0.85 | TDP1 (0.52) | PDE4APDE4BPDE4CPDE4DTSHR | |
| Hydrochloric Acid SCHEMBL10569609 | 0.85 | TDP1 (0.52) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL10567307 | 0.83 | MAPT (0.48) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL10567311 | 0.83 | MAPT (0.48) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL10725789 | 0.83 | MAPT (0.48) | PDE4APDE4BPDE4CPDE4DTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0166564-A2 | Pyrimidone derivatives, preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-02 | — | — | EP | disclosed |