SCHEMBL109722

SCHEMBL109722

O=[C]NCC(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1766687 0.77
SCHEMBL21597566 0.77
SCHEMBL8009144 0.77
SCHEMBL8012014 0.77
SCHEMBL20899743 0.77
SCHEMBL3325882 0.73
SCHEMBL3842675 0.71
SCHEMBL16290223 0.69
SCHEMBL9829260 0.69
SCHEMBL269931 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 712 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12012409-B2 Bicyclic heterocycles as FGFR inhibitors INCYTE CORPORATION (US) 2024-06-18 US claimed
WO-2024068519-A1 3-(HETERO)ARYL-5-CHLORODIFLUOROMETHYL-1,2,4-OXADIAZOLE AS FUNGICIDE BAYER AKTIENGESELLSCHAFT (DE) 2024-04-04 WO claimed
EP-3864015-B1 PROCESS FOR THE PREPARATION OF IMIDAZOLE DERIVATEIVES BAYER AG (DE) 2023-05-10 EP claimed
CN-110312718-B Heterocyclene derivatives as pest control agents 拜耳公司 2023-02-28 CN claimed
EP-3864016-B1 PROCESS FOR PREPARING SUBSTITUTED IMIDAZOLE DERIVATIVES BAYER AG (DE) 2022-09-14 EP claimed
US-11331314-B2 Amine substituted triazole derivatives and uses thereof BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2022-05-17 US claimed
CN-113979887-A Synthetic method of aromatic amine carboxylic acid derivative 北京亦农生物科技有限公司 2022-01-28 CN claimed
US-11230540-B2 Substituted triazole derivatives and uses thereof BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2022-01-25 US claimed
US-20220009930-A1 PROCESS FOR PREPARING IMIDAZOLE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2022-01-13 US claimed
US-20210380611-A1 PROCESS FOR PREPARING SUBSTITUTED IMIDAZOLE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2021-12-09 US claimed
US-20020032238-A1 Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-03-14 US claimed
WO-2002004403-A1 BIPHENYLCARBOXYLIC ACID AMIDES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-01-17 WO claimed
US-6127391-A A PEPTIDE MIMETIC COMPOUND FOR STIMULATING THE RELEASE OF GROWTH HORMONE FROM THE PITUITARY NOVO NORDISK A/S (DK) 2000-10-03 US claimed
EP-0869974-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1998-10-14 EP claimed
WO-1997023508-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1997-07-03 WO claimed
EP-0630382-B1 LACTAM DIPEPTIDES HAVING HLE INHIBITING ACTIVITY ZENECA LTD (GB) 1997-02-26 EP claimed
EP-0630382-A1 LACTAM DIPEPTIDES HAVING HLE INHIBITING ACTIVITY. ZENECA LTD (GB) 1994-12-28 EP claimed
WO-1993021212-A1 LACTAM DIPEPTIDES HAVING HLE INHIBITING ACTIVITY ZENECA LIMITED (GB) 1993-10-28 WO claimed
US-4916148-A AROMATASE INHIBITORS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-04-10 US claimed
EP-0316097-A1 Naphtho(2,1-b)furan derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-05-17 EP claimed