Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10974637 | 1.00 | TUBB1 (0.61) | TUBB1PTGS1PTGS2ALOX5ALDH1A1 | |
| SCHEMBL11213877 | 0.88 | TTR (0.61) | TUBB1PTGS1PTGS2ALOX5ALDH1A1 | |
| SCHEMBL16105805 | 0.88 | TTR (0.61) | TUBB1PTGS1PTGS2ALOX5ALDH1A1 | |
| SCHEMBL29712858 | 0.88 | TTR (0.61) | TUBB1PTGS1PTGS2ALOX5ALDH1A1 | |
| SCHEMBL11000196 | 0.88 | TTR (0.61) | TUBB1PTGS1PTGS2ALOX5ALDH1A1 | |
| SCHEMBL19250176 | 0.87 | TUBB1 (0.50) | TUBB1PTGS1PTGS2ALOX5ALDH1A1 | |
| SCHEMBL3628189 | 0.87 | TUBB1 (0.50) | TUBB1PTGS1PTGS2ALOX5ALDH1A1 | |
| SCHEMBL13825595 | 0.86 | TUBB1 (0.50) | TUBB1PTGS1PTGS2ALOX5ALDH1A1 | |
| SCHEMBL18130043 | 0.86 | TUBB1 (0.58) | TUBB1PTGS1PTGS2ALOX5ALDH1A1 | |
| SCHEMBL30940359 | 0.86 | TUBB1 (0.58) | TUBB1PTGS1PTGS2ALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4533505-A | REACTION OF ETHYLENE IWITH ACID HALIDES IN THE PRESENCE OF A BASE AND A PALLADIUM CATALYST | CIBA-GEIGY CORPORATION (US) | 1985-08-06 | — | — | US | disclosed |
| EP-0062005-B1 | PROCESS FOR THE MANUFACTURE OF STYRENE AND/OR STILBENE DERIVATIVES | CIBA-GEIGY AG (CH) | 1985-06-26 | — | — | EP | disclosed |
| EP-0062005-A1 | Process for the manufacture of styrene and/or stilbene derivatives | CIBA-GEIGY AG (CH) | 1982-10-06 | — | — | EP | disclosed |