SCHEMBL10976321

SCHEMBL10976321

C/C(=C\c1ccc(N)cc1)C(=O)/C(C)=C/c1ccc(N)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.47
AKR1C3 P42330 1/20 0.47
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 1/20 0.41
APP P05067 2/20 0.40
RAB9A P51151 4/20 0.38
NPC1 O15118 3/20 0.38
MAPT P10636 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
GLA P06280 1/20 0.38
POLB P06746 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
GFER P55789 1/20 0.38
CYP2C9 P11712 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
NFKB1 P19838 1/20 0.38
HTT P42858 1/20 0.38
NFKB2 Q00653 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10976324 1.00 CYP19A1 (0.47) CYP19A1AKR1C3ALDH1A1KDM4EAPP
SCHEMBL10078746 0.90 AKR1C3 (0.52) CYP19A1AKR1C3ALDH1A1KDM4EAPP
SCHEMBL28741095 0.88 CYP19A1 (0.42) CYP19A1AKR1C3ALDH1A1KDM4EAPP
SCHEMBL9065444 0.85 AKR1C3 (0.45) CYP19A1AKR1C3ALDH1A1KDM4EAPP
SCHEMBL9065442 0.85 AKR1C3 (0.45) CYP19A1AKR1C3ALDH1A1KDM4EAPP
SCHEMBL3033605 0.85 AKR1C3 (0.67) CYP19A1AKR1C3ALDH1A1KDM4EAPP
SCHEMBL3033607 0.85 AKR1C3 (0.67) CYP19A1AKR1C3ALDH1A1KDM4EAPP
Hydrochloric Acid SCHEMBL1058186 0.83 AKR1C3 (0.64) CYP19A1AKR1C3ALDH1A1KDM4EAPP
Hydrochloric Acid SCHEMBL1058183 0.83 AKR1C3 (0.64) CYP19A1AKR1C3ALDH1A1KDM4EAPP
SCHEMBL1259189 0.80 CYP19A1 (0.42) CYP19A1AKR1C3MAPTTDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0068808-B1 PHOTORESIST COMPOSITION JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1985-06-05 EP claimed
EP-0068808-A2 Photoresist composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-01-05 EP claimed
WO-2024156230-A1 FULL-BIO-BASED ARYL DIAMINE FLAME RETARDANT AND FULL-BIO-BASED ARYL DIAMINE POLYIMIDE THIN FILM 南京工业大学 2024-08-02 WO disclosed
EP-0068808-B1 PHOTORESIST COMPOSITION JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1985-06-05 EP disclosed
EP-0068808-A2 Photoresist composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-01-05 EP disclosed