Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 13/20 | 0.70 |
| ▸ | RARB | P10826 | 12/20 | 0.70 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | CHRND | Q07001 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 10/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10977309 | 1.00 | RARG (0.70) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10977312 | 1.00 | RARG (0.70) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10934181 | 0.87 | RARG (0.68) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10934189 | 0.87 | RARG (0.68) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10934173 | 0.87 | RARG (0.68) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10936009 | 0.86 | RARG (0.51) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10936000 | 0.86 | RARG (0.51) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10936038 | 0.85 | RARG (0.65) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10936042 | 0.85 | RARG (0.65) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10936046 | 0.85 | RARG (0.65) | RARGRARBCHRNA1CHRNGCHRNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155940-A1 | BENZONORBORNENYL, BENZOPYRANYL AND BENZOTHIOPYRANYL RETINOIC ACID ANALOGUES | SRI INTERNATIONAL (US) | 1985-10-02 | — | — | EP | disclosed |
| WO-1985000806-A1 | BENZONORBORNENYL, BENZOPYRANYL AND BENZOTHIOPYRANYL RETINOIC ACID ANALOGUES | SRI INTERNATIONAL (US) | 1985-02-28 | — | — | WO | disclosed |