Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10978460 | 1.00 | TSHR (0.48) | TSHRTAAR1LMNAHTR1AALDH1A1 | |
| SCHEMBL15892812 | 0.98 | TSHR (0.47) | TSHRTAAR1LMNAHTR1AALDH1A1 | |
| SCHEMBL15892809 | 0.98 | TSHR (0.47) | TSHRTAAR1LMNAHTR1AALDH1A1 | |
| SCHEMBL15892796 | 0.94 | TSHR (0.42) | TSHRTAAR1LMNAHTR1AALDH1A1 | |
| SCHEMBL15892795 | 0.94 | TSHR (0.42) | TSHRTAAR1LMNAHTR1AALDH1A1 | |
| SCHEMBL14655081 | 0.92 | SLC6A2 (0.44) | TSHRTAAR1LMNAHTR1AALDH1A1 | |
| SCHEMBL291876 | 0.92 | SLC6A2 (0.44) | TSHRTAAR1LMNAHTR1AALDH1A1 | |
| SCHEMBL10755388 | 0.92 | SLC6A2 (0.44) | TSHRTAAR1LMNAHTR1AALDH1A1 | |
| SCHEMBL292471 | 0.92 | TSHR (0.41) | TSHRTAAR1LMNAHTR1AALDH1A1 | |
| SCHEMBL27755429 | 0.92 | TSHR (0.41) | TSHRTAAR1LMNAHTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496579-A | AMINATION WITH AMMONIA OR PRIMARY AMINE; ANTIDEPRESANT | GLAXO GROUP LIMITED (GB) | 1985-01-29 | — | — | US | disclosed |