Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | PPARG | P37231 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | HTR2A | P28223 | 2/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.64 |
| ▸ | CNR1 | P21554 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11640865 | 0.93 | PPARA (0.72) | PPARACYP1A2CYP3A4PPARGMEN1 | |
| SCHEMBL10975369 | 0.92 | PPARA (0.61) | PPARACYP1A2CYP3A4PPARGMEN1 | |
| SCHEMBL24177730 | 0.89 | PPARA (0.68) | PPARACYP1A2CYP3A4PPARGMEN1 | |
| SCHEMBL12573590 | 0.89 | PPARA (0.67) | PPARACYP1A2CYP3A4PPARGMEN1 | |
| SCHEMBL12573937 | 0.88 | PPARA (0.66) | PPARACYP1A2CYP3A4PPARGMEN1 | |
| SCHEMBL12573936 | 0.86 | PPARA (0.86) | PPARACYP1A2CYP3A4PPARGMEN1 | |
| SCHEMBL12573598 | 0.86 | PPARA (0.60) | PPARACYP1A2CYP3A4PPARGMEN1 | |
| SCHEMBL3284010 | 0.86 | PPARA (0.60) | PPARACYP1A2CYP3A4PPARGMEN1 | |
| SCHEMBL12573938 | 0.86 | PPARA (0.63) | PPARACYP1A2CYP3A4PPARGMEN1 | |
| SCHEMBL15674282 | 0.85 | PPARA (0.65) | PPARACYP1A2CYP3A4PPARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4515809-A | ANTICHOLESTEROL | ALFA FARMACEUTICI S.P.A. (IT) | 1985-05-07 | — | — | US | disclosed |
| US-4378373-A | Derivatives of benzoylphenoxyalkanoic acids having normolipemizing activity | ALFA FARMACEUTICI S.P.A. (IT) | 1983-03-29 | — | — | US | disclosed |
| US-4296125-A | Derivatives of benzoylphenoxyalkanoic acids having normolipemizing activity | ALPHA FARMACEUTICI S.P.A. (IT) | 1981-10-20 | — | — | US | disclosed |