Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.46 |
| ▸ | PGR | P06401 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.38 |
| ▸ | APAF1 | O14727 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.38 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10986613 | 0.95 | NR1I2 (0.45) | NR1I2PGRTDP1APAF1APEX1 | |
| SCHEMBL10985166 | 0.95 | NR1I2 (0.45) | NR1I2PGRTDP1APAF1APEX1 | |
| SCHEMBL10981443 | 0.95 | NR1I2 (0.45) | NR1I2PGRTDP1APAF1APEX1 | |
| SCHEMBL10993679 | 0.94 | NR1I2 (0.43) | NR1I2PGRTDP1APAF1APEX1 | |
| SCHEMBL10986735 | 0.93 | NR1I2 (0.53) | NR1I2PGRTDP1APAF1APEX1 | |
| SCHEMBL10784664 | 0.93 | NR1I2 (0.43) | NR1I2PGRTDP1APAF1APEX1 | |
| SCHEMBL10856050 | 0.92 | NR1I2 (0.44) | NR1I2PGRTDP1APAF1APEX1 | |
| SCHEMBL10980037 | 0.92 | NR1I2 (0.44) | NR1I2PGRTDP1APAF1APEX1 | |
| SCHEMBL10831426 | 0.92 | NR1I2 (0.43) | NR1I2PGRTDP1APAF1APEX1 | |
| SCHEMBL10994225 | 0.91 | NR1I2 (0.44) | NR1I2PGRTDP1APAF1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025199-B1 | CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-31 | — | — | EP | claimed |
| EP-0025199-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-03-18 | — | — | EP | claimed |
| US-4529802-A | A carboxylated thiazole oxime compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-07-16 | — | — | US | disclosed |
| EP-0025199-B1 | CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-31 | — | — | EP | disclosed |
| US-4394384-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-07-19 | — | — | US | disclosed |
| EP-0025199-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-03-18 | — | — | EP | disclosed |