Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 19/20 | 0.73 |
| ▸ | SLC6A3 | Q01959 | 19/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2049 | 0.99 | SLC6A4 (0.71) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL2793 | 0.85 | SLC6A4 (0.57) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL3520692 | 0.84 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL2434 | 0.83 | SLC6A4 (0.54) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL11115868 | 0.80 | SLC6A4 (0.58) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL10840419 | 0.80 | SLC6A4 (0.78) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL3521787 | 0.80 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL2409 | 0.79 | SLC6A4 (0.76) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL2805 | 0.78 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8042323 | 0.78 | SLC6A4 (0.91) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4522828-A | CYCLOBUTYLALKYLAMINE COMPOUNDS, ANTIDEPRESSANTS | THE BOOTS COMPANY PLC (GB) | 1985-06-11 | — | — | US | claimed |