Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 3/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | NAAA | Q02083 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10938443 | 1.00 | KDM5A (0.43) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL10936923 | 0.89 | KDM5A (0.48) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL10940711 | 0.89 | KDM5A (0.48) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL10780276 | 0.89 | KDM5A (0.48) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL10978610 | 0.89 | KDM5A (0.48) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL10783292 | 0.89 | KDM5A (0.48) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL10781633 | 0.89 | KDM5A (0.48) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL10783114 | 0.89 | KDM5A (0.48) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL10780211 | 0.89 | KDM5A (0.48) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL10942470 | 0.87 | KDM5A (0.45) | KDM5APHF8KDM2AKDM4CKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4554359-A | 3-Substituted pentanedioic acids and derivatives thereof | G. D. SEARLE & CO. (US) | 1985-11-19 | — | — | US | disclosed |
| EP-0156100-A2 | 3-Substituted hydroxypentanedioic acids, -hemiesters or -anhydrides | G.D. Searle & Co. (US) | 1985-10-02 | — | — | EP | disclosed |