Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10984791 | 1.00 | TP53 (0.43) | TP53TSHRPLA2G4BALDH1A1MEN1 | |
| SCHEMBL10986399 | 1.00 | TP53 (0.43) | TP53TSHRPLA2G4BALDH1A1MEN1 | |
| SCHEMBL10987410 | 1.00 | TP53 (0.43) | TP53TSHRPLA2G4BALDH1A1MEN1 | |
| SCHEMBL10982389 | 1.00 | TP53 (0.43) | TP53TSHRPLA2G4BALDH1A1MEN1 | |
| SCHEMBL10992398 | 1.00 | TP53 (0.43) | TP53TSHRPLA2G4BALDH1A1MEN1 | |
| SCHEMBL10982382 | 1.00 | TP53 (0.43) | TP53TSHRPLA2G4BALDH1A1MEN1 | |
| SCHEMBL10992428 | 1.00 | TP53 (0.43) | TP53TSHRPLA2G4BALDH1A1MEN1 | |
| SCHEMBL10984785 | 1.00 | TP53 (0.43) | TP53TSHRPLA2G4BALDH1A1MEN1 | |
| SCHEMBL10985156 | 1.00 | TP53 (0.43) | TP53TSHRPLA2G4BALDH1A1MEN1 | |
| SCHEMBL10986404 | 1.00 | TP53 (0.43) | TP53TSHRPLA2G4BALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4493843-A | Indole and indoline carboxylic acid compounds and method of use | MAY & BAKER LIMITED (GB) | 1985-01-15 | — | — | US | disclosed |
| EP-0042298-B1 | INDOLE AND INDOLINE DERIVATIVES | MAY & BAKER LIMITED (GB) | 1984-09-12 | — | — | EP | disclosed |
| EP-0042298-A1 | Indole and indoline derivatives | MAY & BAKER LIMITED (GB) | 1981-12-23 | — | — | EP | disclosed |