SCHEMBL10985405

SCHEMBL10985405

Cc1cc(C(=O)Nc2cccc(N)c2O)ccc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
RAB9A P51151 4/20 0.47
NPC1 O15118 3/20 0.47
HDAC2 Q92769 6/20 0.46
HDAC1 Q13547 6/20 0.46
HDAC3 O15379 4/20 0.46
MAPK1 P28482 1/20 0.46
CASP3 P42574 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
HDAC4 P56524 2/20 0.46
HDAC7 Q8WUI4 2/20 0.46
HDAC10 Q969S8 2/20 0.46
HDAC11 Q96DB2 2/20 0.46
HDAC8 Q9BY41 2/20 0.46
HDAC6 Q9UBN7 2/20 0.46
HDAC9 Q9UKV0 2/20 0.46
HDAC5 Q9UQL6 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10766253 0.84 NPC1 (0.66) MEN1KMT2ARAB9ANPC1HDAC1
SCHEMBL10401801 0.79 S1PR4 (0.60) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL17744813 0.79 KCNK3 (0.61) MEN1KMT2ARAB9ATOP1
SCHEMBL11427941 0.77 MEN1 (0.41) MEN1KMT2ARAB9ANPC1CASP3
SCHEMBL11438686 0.77 HPSE (0.43) MEN1KMT2ARAB9ASENP7MAPT
SCHEMBL17744810 0.77 NPC1 (0.58) MEN1KMT2ARAB9ANPC1HDAC1
SCHEMBL29904860 0.77 MAPT (0.68) MEN1KMT2ARAB9ANPC1HDAC1
SCHEMBL28395330 0.77 MAPT (0.68) MEN1KMT2ARAB9ANPC1HDAC1
SCHEMBL11428597 0.76 CD40 (0.45) MEN1KMT2ARAB9ANPC1HDAC2
SCHEMBL11433575 0.76 CD40 (0.48) MEN1KMT2ARAB9ANPC1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0034498-B1 ELECTROPHOTOGRAPHIC LIGHT-SENSITIVE MEDIA Canon Inc. (JP) 1985-09-25 EP disclosed
US-4356243-A Electrophotographic media with benzoxazole group containing dis-azo compound COPYER CO., LTD. (JP) 1982-10-26 US disclosed
EP-0034498-A2 Electrophotographic light-sensitive media Canon Inc. (JP) 1981-08-26 EP disclosed