Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 5/20 | 0.44 |
| ▸ | SRC | P12931 | 5/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 5/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.44 |
| ▸ | KDR | P35968 | 5/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10984515 | 0.88 | FGFR1 (0.43) | FGFR1SRCFGFR2FGFR4FGFR3 | |
| SCHEMBL14692428 | 0.87 | FGFR1 (0.51) | FGFR1SRCFGFR2FGFR4FGFR3 | |
| SCHEMBL3374482 | 0.81 | FGFR1 (0.62) | FGFR1SRCFGFR2FGFR4FGFR3 | |
| SCHEMBL14692631 | 0.76 | MAPK14 (0.52) | FGFR1SRCFGFR2FGFR4FGFR3 | |
| SCHEMBL8047299 | 0.75 | RIPK2 (0.56) | FGFR1SRCFGFR2FGFR4FGFR3 | |
| SCHEMBL10708284 | 0.75 | NOTUM (0.37) | FGFR1SRCFGFR2FGFR4FGFR3 | |
| SCHEMBL14692467 | 0.74 | PTPN1 (0.56) | FGFR1SRCFGFR2FGFR4FGFR3 | |
| SCHEMBL15933282 | 0.74 | SCN9A (0.49) | FGFR1SRCFGFR2FGFR4FGFR3 | |
| SCHEMBL3374632 | 0.74 | PTPN1 (0.69) | PTPN1RIPK2MAPK14KDM4ENPC1 | |
| SCHEMBL10365970 | 0.73 | SCN9A (0.48) | FGFR1SRCFGFR2FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034945-B1 | N-PHENYLPYRAZOLE DERIVATIVES | MAY & BAKER LIMITED (GB) | 1985-08-07 | — | — | EP | disclosed |
| US-4496390-A | WEED-CONTRTOLLING HERBICIDES | MAY & BAKER LIMITED (GB) | 1985-01-29 | — | — | US | disclosed |
| EP-0034945-A2 | N-phenylpyrazole derivatives | MAY & BAKER LIMITED (GB) | 1981-09-02 | — | — | EP | disclosed |