Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 1.00 |
| ▸ | GSK3A | P49840 | 2/20 | 1.00 |
| ▸ | GSK3B | P49841 | 2/20 | 1.00 |
| ▸ | PIM3 | Q86V86 | 2/20 | 1.00 |
| ▸ | PRKD3 | O94806 | 1/20 | 1.00 |
| ▸ | IRAK1 | P51617 | 1/20 | 1.00 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 1.00 |
| ▸ | DYRK1A | Q13627 | 1/20 | 1.00 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 1.00 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.71 |
| ▸ | TOP1 | P11387 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10976982 | 0.88 | PIM1 (0.79) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL9617590 | 0.87 | PIM1 (0.77) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL9617588 | 0.87 | PIM1 (0.77) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL9693620 | 0.87 | PIM1 (0.77) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL10979020 | 0.85 | PIM1 (0.73) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL10976483 | 0.84 | PIM1 (0.73) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL9615164 | 0.84 | PIM1 (0.72) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL10979207 | 0.84 | PIM1 (0.72) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL10976381 | 0.83 | PIM1 (0.71) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL10976636 | 0.83 | PIM1 (0.71) | PIM1GSK3AGSK3BPIM3PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4550104-A | Antibacterial thiazolo-quinolines and thiazolo-naphthyridines | WARNER-LAMBERT COMPANY (US) | 1985-10-29 | — | — | US | claimed |
| US-4550104-A | Antibacterial thiazolo-quinolines and thiazolo-naphthyridines | WARNER-LAMBERT COMPANY (US) | 1985-10-29 | — | — | US | disclosed |