Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | IL2 | P60568 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL471881 | 0.86 | KDM4E (0.62) | KDM4EIL2HRH3LMNAMAPT | |
| SCHEMBL28714649 | 0.83 | KDM4E (0.47) | KDM4EIL2HRH3LMNAMAPT | |
| SCHEMBL20410843 | 0.83 | KDM4E (0.59) | KDM4EIL2HRH3LMNAMAPT | |
| SCHEMBL4159068 | 0.83 | KDM4E (0.54) | KDM4EIL2HRH3LMNAMAPT | |
| SCHEMBL20410735 | 0.82 | KDM4E (0.54) | KDM4EIL2HRH3LMNAMAPT | |
| SCHEMBL20396188 | 0.81 | KDM4E (0.53) | KDM4EIL2HRH3LMNAMAPT | |
| SCHEMBL29689817 | 0.81 | KDM4E (0.53) | KDM4EIL2HRH3LMNAMAPT | |
| SCHEMBL30863841 | 0.80 | KDM4E (0.56) | KDM4EIL2HRH3LMNAMAPT | |
| SCHEMBL1338857 | 0.80 | KDM4E (0.56) | KDM4EIL2HRH3LMNAMAPT | |
| SCHEMBL11486647 | 0.80 | KDM4E (0.51) | KDM4EIL2HRH3LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536591-A | Insecticidal [1,1'-biphenyl]-3-ylmethyl esters | FMC CORPORATION (US) | 1985-08-20 | — | — | US | disclosed |
| EP-0063374-B1 | SUBSTITUTED BIPHENYL COMPOUNDS | FMC Corporation (US) | 1984-02-22 | — | — | EP | disclosed |
| US-4402973-A | Insecticidal (1,1'-biphenyl)-3-ylmethyl esters | FMC CORPORATION (US) | 1983-09-06 | — | — | US | disclosed |
| EP-0020685-B1 | INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED (1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS | FMC Corporation (US) | 1983-06-15 | — | — | EP | disclosed |
| EP-0063374-A1 | Substituted biphenyl compounds | FMC Corporation (US) | 1982-10-27 | — | — | EP | disclosed |
| US-4329518-A | INSECTICIDES, ACARICIDES, MITICIDES | FMC CORPORATION (US) | 1982-05-11 | — | — | US | disclosed |
| EP-0049977-A1 | Insecticidal (1,1'-biphenyl)-3-ylmethyl esters, their production and use and compositions containing them | FMC Corporation (US) | 1982-04-21 | — | — | EP | disclosed |
| EP-0020685-A4 | INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED (1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS. | FMC CORP (US) | 1981-07-16 | — | — | EP | disclosed |
| EP-0020685-A1 | INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED (1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS. | FMC CORP (US) | 1981-01-07 | — | — | EP | disclosed |
| US-4214004-A | MITICIDES | FMC CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| WO-1980001163-A1 | INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED(1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS | FMC CORP (US) | 1980-06-12 | — | — | WO | disclosed |