⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8286807 | 0.63 | — | — | |
| SCHEMBL7459968 | 0.62 | — | — | |
| SCHEMBL1898175 | 0.62 | — | — | |
| SCHEMBL574735 | 0.62 | — | — | |
| SCHEMBL5562985 | 0.62 | — | — | |
| SCHEMBL4199833 | 0.62 | — | — | |
| SCHEMBL12786313 | 0.62 | — | — | |
| SCHEMBL6761700 | 0.62 | — | — | |
| SCHEMBL14252552 | 0.62 | — | — | |
| SCHEMBL4280209 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590982-B1 | PROTEIN KINASE INHIBITORS AND METHODS OF TREATMENT | THE WALTER AND ELIZA HALL INST OF MEDICAL RES (AU) | 2017-08-23 | — | — | EP | disclosed |
| EP-2149571-A1 | MUTILIN DERIVATIVE HAVING HETEROCYCLIC AROMATIC RING CARBOXYLIC ACID STRUCTURE IN SUBSTITUENT AT 14-POSITION | Kyorin Pharmaceutical Co., Ltd. (JP) | 2010-02-03 | — | — | EP | disclosed |
| US-4501855-A | CARBOXY OR AMINO CHAIN-TERMINATED ADDITION COPOLYMER CONTAINING TERT-AMINE MONOMER REACTED WITH SOLUBLE POLYMER CONTAINING CARBOXY OR AMINE-REACTIVE FUNCTIONALITY | DESOTO, INC. (US) | 1985-02-26 | — | — | US | disclosed |