SCHEMBL10987643

SCHEMBL10987643

O=C1OCCCCCCOCCCCCCOC1=O

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
CA1 P00915 1/20 0.43
CA9 Q16790 1/20 0.43
LMNA P02545 3/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
PGR P06401 2/20 0.31
SMN1; SMN2 Q16637 3/20 0.31
CRHBP P24387 2/20 0.31
CRHR2 Q13324 2/20 0.31
HTT P42858 1/20 0.31
NAMPT P43490 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28886215 0.91 CA1 (0.50) ALDH1A1CA1CA9LMNATP53
SCHEMBL17672300 0.91 CA1 (0.50) ALDH1A1CA1CA9LMNATP53
SCHEMBL28379193 0.91 CA1 (0.50) ALDH1A1CA1CA9LMNATP53
SCHEMBL31492941 0.91 CA1 (0.50) ALDH1A1CA1CA9LMNATP53
SCHEMBL493682 0.91 CA1 (0.50) ALDH1A1CA1CA9LMNATP53
SCHEMBL3093303 0.91 CA1 (0.50) ALDH1A1CA1CA9LMNATP53
SCHEMBL4302406 0.91 CA1 (0.50) ALDH1A1CA1CA9LMNATP53
SCHEMBL9788227 0.91 CA1 (0.50) ALDH1A1CA1CA9LMNATP53
Hydrogen Sulfide SCHEMBL27672065 0.88 CA1 (0.48) ALDH1A1CA1CA9LMNATP53
SCHEMBL493857 0.87 CA1 (0.53) ALDH1A1CA1CA9LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4499288-A THERMAL DEPOLYMERIZATION OF POLYESTERS; EFFICIENCY NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1985-02-12 US disclosed
US-4393223-A THERMAL DEPOLYMERIZATION OF POLYESTERS EMERY INDUSTRIES, INC. (US) 1983-07-12 US disclosed
US-4331603-A Process for improving the fragrance properties of macrocyclic compounds obtained by thermal depolymerization EMERY INDUSTRIES, INC. (US) 1982-05-25 US disclosed
US-4218379-A Process for the production of macrocyclic esters EMERY INDUSTRIES, INC. (US) 1980-08-19 US disclosed
US-4165321-A Process for the production of heterocyclic compounds HENKEL CORPORATION, A DE CORP. 1979-08-21 US disclosed