Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | NAAA | Q02083 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8984086 | 0.98 | TSHR (0.62) | TSHRNAAACES2MEN1THRB | |
| SCHEMBL9955169 | 0.93 | TSHR (0.72) | TSHRNAAACES2EPHX1RAD52 | |
| SCHEMBL457867 | 0.93 | TSHR (0.72) | TSHRNAAACES2EPHX1RAD52 | |
| SCHEMBL2456648 | 0.93 | TSHR (0.72) | TSHRNAAACES2EPHX1RAD52 | |
| SCHEMBL2456606 | 0.93 | TSHR (0.72) | TSHRNAAACES2EPHX1RAD52 | |
| SCHEMBL9955486 | 0.93 | TSHR (0.72) | TSHRNAAACES2EPHX1RAD52 | |
| SCHEMBL15987888 | 0.93 | TSHR (0.72) | TSHRNAAACES2EPHX1RAD52 | |
| SCHEMBL2454309 | 0.93 | TSHR (0.72) | TSHRNAAACES2EPHX1RAD52 | |
| SCHEMBL9955198 | 0.93 | TSHR (0.72) | TSHRNAAACES2EPHX1RAD52 | |
| SCHEMBL6834546 | 0.93 | TSHR (0.72) | TSHRNAAACES2EPHX1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499288-A | THERMAL DEPOLYMERIZATION OF POLYESTERS; EFFICIENCY | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1985-02-12 | — | — | US | disclosed |
| US-4393223-A | THERMAL DEPOLYMERIZATION OF POLYESTERS | EMERY INDUSTRIES, INC. (US) | 1983-07-12 | — | — | US | disclosed |
| US-4331603-A | Process for improving the fragrance properties of macrocyclic compounds obtained by thermal depolymerization | EMERY INDUSTRIES, INC. (US) | 1982-05-25 | — | — | US | disclosed |
| US-4218379-A | Process for the production of macrocyclic esters | EMERY INDUSTRIES, INC. (US) | 1980-08-19 | — | — | US | disclosed |
| US-4165321-A | Process for the production of heterocyclic compounds | HENKEL CORPORATION, A DE CORP. | 1979-08-21 | — | — | US | disclosed |