Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.54 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.54 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.54 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.54 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.54 |
| ▸ | RAF1 | P04049 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | GCGR | P47871 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8356566 | 0.94 | MAPT (0.63) | NOX1MAPTTP53MAPK13MAPK12 | |
| SCHEMBL3455232 | 0.82 | NOX1 (0.77) | NOX1MAPTTP53MAPK13MAPK12 | |
| SCHEMBL6464698 | 0.81 | NOX1 (0.74) | NOX1MAPTTP53MAPK13MAPK12 | |
| SCHEMBL9749306 | 0.81 | HPGD (0.62) | NOX1MAPTTP53MAPK13MAPK12 | |
| SCHEMBL15400824 | 0.81 | NOX1 (0.85) | NOX1MAPTTP53MAPK13MAPK12 | |
| SCHEMBL8008805 | 0.81 | NOX1 (0.85) | NOX1MAPTTP53MAPK13MAPK12 | |
| SCHEMBL5441279 | 0.80 | NOX1 (0.52) | NOX1MAPTTP53MAPK13MAPK12 | |
| SCHEMBL5434851 | 0.79 | NOX1 (0.59) | NOX1MAPTTP53MAPK13MAPK12 | |
| SCHEMBL10993607 | 0.79 | NOX1 (0.59) | NOX1MAPTTP53MAPK13MAPK12 | |
| SCHEMBL10814349 | 0.78 | NOX1 (0.57) | NOX1MAPTTP53MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4503065-A | ANTIARTHRITIC, ANALGESIC | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-03-05 | — | — | US | disclosed |