Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127342 | 0.90 | MAPT (0.68) | MAPTKCNH2HRH3 | |
| SCHEMBL7787166 | 0.90 | MAPT (0.68) | MAPTKCNH2HRH3 | |
| SCHEMBL9166930 | 0.90 | MAPT (0.68) | MAPTKCNH2HRH3 | |
| SCHEMBL7120513 | 0.90 | MAPT (0.68) | MAPTKCNH2HRH3 | |
| SCHEMBL7130261 | 0.88 | MAPT (0.70) | MAPTKCNH2HRH3 | |
| SCHEMBL14367557 | 0.85 | MAPT (0.61) | MAPTKCNH2HRH3 | |
| SCHEMBL8252658 | 0.85 | MAPT (0.61) | MAPTKCNH2HRH3 | |
| SCHEMBL8252356 | 0.85 | MAPT (0.61) | MAPTKCNH2HRH3 | |
| SCHEMBL8722872 | 0.82 | KCNH2 (0.59) | MAPTKCNH2 | |
| SCHEMBL7764341 | 0.82 | KCNH2 (0.59) | MAPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4491583-A | HETEROCYCLIC UREA COMPOUNDS | PFIZER INC. (US) | 1985-01-01 | — | — | US | disclosed |
| US-4258061-A | TO COMBAT VIRAL DISEASE | PFIZER INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4087552-A | ANTIVIRAL | PFIZER INC. (US) | 1978-05-02 | — | — | US | disclosed |
| US-4034040-A | Xylene-diamines as antiviral agents | PFIZER INC. (US) | 1977-07-05 | — | — | US | disclosed |