Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 5/20 | 0.45 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
| ▸ | ICMT | O60725 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435158 | 0.96 | KDM5A (0.47) | KDM5APHF8KDM4CPOLBPOLA1 | |
| SCHEMBL8337930 | 0.96 | KDM5A (0.47) | KDM5APHF8KDM4CPOLBPOLA1 | |
| SCHEMBL63203 | 0.96 | KDM5A (0.47) | KDM5APHF8KDM4CPOLBPOLA1 | |
| SCHEMBL19032377 | 0.93 | KDM5A (0.45) | KDM5APHF8KDM4CPOLBPOLA1 | |
| SCHEMBL19032563 | 0.93 | KDM5A (0.45) | KDM5APHF8KDM4CPOLBPOLA1 | |
| SCHEMBL18954314 | 0.93 | KDM5A (0.45) | KDM5APHF8KDM4CPOLBPOLA1 | |
| SCHEMBL19032471 | 0.93 | KDM5A (0.45) | KDM5APHF8KDM4CPOLBPOLA1 | |
| SCHEMBL8335342 | 0.92 | KDM5A (0.47) | KDM5APHF8KDM4CPOLBPOLA1 | |
| SCHEMBL15880164 | 0.92 | KDM5A (0.47) | KDM5APHF8KDM4CPOLBPOLA1 | |
| SCHEMBL19032444 | 0.92 | KDM5A (0.47) | KDM5APHF8KDM4CPOLBPOLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4491583-A | HETEROCYCLIC UREA COMPOUNDS | PFIZER INC. (US) | 1985-01-01 | — | — | US | disclosed |
| US-4258061-A | TO COMBAT VIRAL DISEASE | PFIZER INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4087552-A | ANTIVIRAL | PFIZER INC. (US) | 1978-05-02 | — | — | US | disclosed |
| US-4034040-A | Xylene-diamines as antiviral agents | PFIZER INC. (US) | 1977-07-05 | — | — | US | disclosed |