Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | P4HB | P07237 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10997388 | 1.00 | MAOB (0.56) | MAOBNFKB1MAOABACE1P4HB | |
| SCHEMBL10929642 | 0.90 | MAOB (0.54) | MAOBNFKB1MAOABACE1P4HB | |
| SCHEMBL10997646 | 0.87 | MAOB (0.59) | MAOBNFKB1MAOABACE1P4HB | |
| SCHEMBL10997649 | 0.87 | MAOB (0.59) | MAOBNFKB1MAOABACE1P4HB | |
| SCHEMBL10995923 | 0.86 | MAOB (0.53) | MAOBNFKB1MAOABACE1P4HB | |
| SCHEMBL10995917 | 0.86 | MAOB (0.53) | MAOBNFKB1MAOABACE1P4HB | |
| SCHEMBL10928926 | 0.85 | MAOB (0.57) | MAOBNFKB1MAOABACE1P4HB | |
| SCHEMBL10928933 | 0.85 | MAOB (0.57) | MAOBNFKB1MAOABACE1P4HB | |
| SCHEMBL10996761 | 0.84 | MAOB (0.55) | MAOBNFKB1MAOABACE1P4HB | |
| SCHEMBL10996758 | 0.84 | MAOB (0.55) | MAOBNFKB1MAOABACE1P4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4544670-A | ANTIPROTOZOA AGENTS, GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | WILLIAM H. RORER, INC. (US) | 1985-10-01 | — | — | US | disclosed |