SCHEMBL10999928

SCHEMBL10999928

CCCCCCC(CC)NCC(O)c1ccc(NS(C)(=O)=O)c(OC)c1

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ADRB3 P13945 20/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9624733 0.88 ADRB3 (0.60) ADRB3
SCHEMBL11035403 0.87 ADRB3 (0.59) ADRB3
SCHEMBL11001335 0.87 ADRB3 (0.59) ADRB3
SCHEMBL9624979 0.82 ADRB3 (0.61) ADRB3
SCHEMBL9624818 0.82 ADRB3 (0.61) ADRB3
SCHEMBL9624946 0.81 ADRB3 (0.56) ADRB3
SCHEMBL10999874 0.78 CACNA1F (0.55) ADRB3
SCHEMBL9624948 0.78 ADRB3 (0.55) ADRB3
SCHEMBL10645824 0.77 ADRB3 (0.64) ADRB3
SCHEMBL10647774 0.75 CACNA1F (0.48) ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0164865-A1 N-(Aminoalkylphenyl)sulfonamides their preparation and therapeutic use THE UPJOHN COMPANY (US) 1985-12-18 EP claimed