Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.49 |
| ▸ | ULK1 | O75385 | 5/20 | 0.47 |
| ▸ | AURKA | O14965 | 3/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.44 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.44 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11001159 | 0.78 | LRRK2 (0.43) | ULK1AURKACCNA2CDK2PLK1 | |
| SCHEMBL10999792 | 0.78 | IGF1R (0.55) | PTK2ULK1AURKAIRAK4KMT2A | |
| SCHEMBL11352065 | 0.74 | KCNH2 (0.51) | PTK2ULK1AURKACCNA2CDK2 | |
| SCHEMBL5030690 | 0.74 | TSHR (0.57) | PTK2ULK1AURKAEGFRALDH1A1 | |
| SCHEMBL10493272 | 0.74 | BCL6 (0.53) | PTK2AURKACDK2PLK3MAP4K4 | |
| SCHEMBL11000276 | 0.74 | STK17B (0.47) | ULK1AURKACDK2ALDH1A1KMT2A | |
| SCHEMBL10997654 | 0.73 | MAPT (0.49) | PTK2AURKACCNA2CDK2PLK1 | |
| SCHEMBL7473390 | 0.72 | AURKA (0.59) | PTK2ULK1AURKAEGFRALDH1A1 | |
| SCHEMBL2195557 | 0.71 | EPHX2 (0.46) | ULK1AURKAEGFRALDH1A1TDP1 | |
| SCHEMBL4562759 | 0.71 | AURKA (0.84) | PTK2AURKACDK2PLK3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31926-E | Penicillins and salts thereof | BOEHRINGER INGELHEIM GMBH (DE) | 1985-06-25 | — | — | US | disclosed |