Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | CASP3 | P42574 | 1/20 | 0.67 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.67 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.67 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.67 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11853387 | 0.85 | KMT2A (0.78) | MAPTKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL9297476 | 0.84 | KMT2A (0.75) | MAPTKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL11005738 | 0.83 | KMT2A (0.66) | MAPTKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL4118204 | 0.81 | NPC1 (0.60) | MAPTKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL4548131 | 0.81 | KMT2A (1.00) | MAPTKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL11045193 | 0.79 | KMT2A (0.71) | MAPTKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL3158731 | 0.78 | P2RY1 (0.66) | KMT2A | |
| SCHEMBL1492931 | 0.77 | KMT2A (0.65) | MAPTKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL2835288 | 0.77 | GAA (0.73) | KMT2AMEN1ALDH1A1NPC1LMNA | |
| SCHEMBL8110954 | 0.75 | GAA (0.75) | KMT2AMEN1ALDH1A1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015110-A2 | Anticoccidial composition, carbanilides and method of preparing them | ELI LILLY AND COMPANY (US) | 1980-09-03 | — | — | EP | claimed |
| EP-0015110-B1 | ANTICOCCIDIAL COMPOSITION, CARBANILIDES AND METHOD OF PREPARING THEM | ELI LILLY AND COMPANY (US) | 1985-08-21 | — | — | EP | disclosed |
| US-4526997-A | Amino, nitro, fluoro substituted carbanilides | DOHERTY GEORGE O P O | 1985-07-02 | — | — | US | disclosed |
| US-4506003-A | Positive-working radiation-sensitive mixture | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-19 | — | — | US | disclosed |
| US-4468380-A | Anticoccidial combinations comprising polyether antibiotics and carbanilides | ELI LILLY AND COMPANY (US) | 1984-08-28 | — | — | US | disclosed |
| EP-0015110-A2 | Anticoccidial composition, carbanilides and method of preparing them | ELI LILLY AND COMPANY (US) | 1980-09-03 | — | — | EP | disclosed |