Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.48 |
| ▸ | CNR1 | P21554 | 10/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11339117 | 0.94 | CNR2 (0.44) | CNR2CNR1 | |
| SCHEMBL843172 | 0.80 | CNR2 (0.57) | CNR2CNR1 | |
| SCHEMBL10991207 | 0.78 | CNR2 (0.56) | CNR2CNR1 | |
| SCHEMBL10996179 | 0.76 | KDM4E (0.46) | CNR2CNR1 | |
| SCHEMBL858856 | 0.76 | CNR2 (0.64) | CNR2CNR1 | |
| SCHEMBL843912 | 0.75 | CNR2 (0.67) | CNR2CNR1 | |
| SCHEMBL10996318 | 0.75 | CNR2 (0.50) | CNR2CNR1 | |
| SCHEMBL10998696 | 0.74 | KDM4E (0.53) | CNR2CNR1 | |
| SCHEMBL859522 | 0.74 | CNR2 (0.66) | CNR2CNR1 | |
| SCHEMBL10990871 | 0.74 | CNR2 (0.66) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003144-A2 | 4-Pyridone-3-carboxylic acid derivatives, pharmaceutical compositions containing them, processes for their preparation, their application | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-07-25 | — | — | EP | claimed |
| US-4549022-A | ANTIBACTERIAL AGENT; STIMULANT ON CENTRAL NERVOUS SYSTEM | HOFFMANN-LA ROCHE INC. (US) | 1985-10-22 | — | — | US | disclosed |
| US-4521535-A | ANTIBACTERIAL AGENTS; STIMULANTS FOR CENTRAL NERVOUS SYSTEM | HOFFMANN-LA ROCHE INC. (US) | 1985-06-04 | — | — | US | disclosed |