Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.83 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.83 |
| ▸ | SSTR5 | P35346 | 8/20 | 0.72 |
| ▸ | EED | O75530 | 2/20 | 0.65 |
| ▸ | HRH1 | P35367 | 2/20 | 0.65 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | MLNR | O43193 | 1/20 | 0.65 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.65 |
| ▸ | EGFR | P00533 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | HLA-A | P04439 | 1/20 | 0.65 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | LCK | P06239 | 1/20 | 0.65 |
| ▸ | FYN | P06241 | 1/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1100874 | 0.93 | KCNH2 (0.83) | KCNH2NR4A2SSTR5EEDHRH1 | |
| SCHEMBL1099818 | 0.92 | KCNH2 (0.79) | KCNH2NR4A2SSTR5EEDHRH1 | |
| Desmetheylastemizole SCHEMBL29601510 | 0.91 | KCNH2 (1.00) | KCNH2NR4A2SSTR5EEDHRH1 | |
| Desmetheylastemizole SCHEMBL1152697 | 0.91 | KCNH2 (1.00) | KCNH2NR4A2SSTR5EEDHRH1 | |
| Desmetheylastemizole SCHEMBL11473379 | 0.90 | KCNH2 (0.98) | KCNH2NR4A2SSTR5EEDHRH1 | |
| Desmetheylastemizole SCHEMBL11473376 | 0.90 | KCNH2 (0.98) | KCNH2NR4A2SSTR5EEDHRH1 | |
| SCHEMBL11263431 | 0.88 | SSTR5 (0.85) | KCNH2NR4A2SSTR5EEDHRH1 | |
| SCHEMBL1100413 | 0.85 | KCNH2 (0.79) | KCNH2NR4A2SSTR5EEDHRH1 | |
| Hydrochloric Acid SCHEMBL11472866 | 0.85 | KCNH2 (0.82) | KCNH2NR4A2SSTR5EEDHRH1 | |
| Bromide SCHEMBL9699693 | 0.82 | KCNH2 (0.67) | KCNH2NR4A2SSTR5EEDHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153385-B2 | Target protein and target gene in drug designing and screening method | REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. (JP) | 2012-04-10 | — | — | US | disclosed |
| US-20100136524-A1 | TARGET PROTEIN AND TARGET GENE IN DRUG DESIGNING AND SCREENING METHOD | REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100136524-A1 | TARGET PROTEIN AND TARGET GENE IN DRUG DESIGNING AND SCREENING METHOD | CHP1, CMA1, CARHSP1 | KCNH2 3897/4885NR4A2 1458/4885SSTR5 3912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.