Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | TTR | P02766 | 1/20 | 0.65 |
| ▸ | PPOX | P50336 | 1/20 | 0.65 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11003429 | 0.95 | TDP1 (0.67) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11005386 | 0.93 | TDP1 (0.65) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11008451 | 0.93 | TDP1 (0.67) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11007247 | 0.93 | TDP1 (0.65) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11004074 | 0.90 | MEN1 (0.73) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11004065 | 0.88 | MEN1 (0.58) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11008339 | 0.87 | TDP1 (0.64) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11008103 | 0.87 | MEN1 (0.68) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11002398 | 0.86 | MEN1 (0.69) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL8582624 | 0.86 | TDP1 (0.71) | MEN1KMT2ATDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4556413-A | POSTEMERGENCE AND PREEMERGENCE HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1985-12-03 | — | — | US | claimed |
| EP-0109575-A2 | Benzoic-acid derivatives, process and means for its production | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-05-30 | — | — | EP | claimed |
| EP-0109575-A2 | Benzoic-acid derivatives, process and means for its production | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-05-30 | — | — | EP | disclosed |