Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.85 |
| ▸ | CA1 | P00915 | 3/20 | 0.69 |
| ▸ | CA2 | P00918 | 3/20 | 0.69 |
| ▸ | CA7 | P43166 | 3/20 | 0.69 |
| ▸ | CA9 | Q16790 | 3/20 | 0.69 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.67 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.62 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.58 |
| ▸ | MTOR | P42345 | 1/20 | 0.58 |
| ▸ | CDK8 | P49336 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL118026 | 0.92 | KDR (1.00) | KDRCA1CA2CA7CA9 | |
| SCHEMBL29364392 | 0.92 | KDR (1.00) | KDRCA1CA2CA7CA9 | |
| SCHEMBL12387674 | 0.90 | KDR (0.78) | KDRCA1CA2CA7CA9 | |
| SCHEMBL11002386 | 0.90 | KDR (0.82) | KDRCA1CA2CA7CA9 | |
| Cloflucarban SCHEMBL119821 | 0.89 | KDR (0.88) | KDRCA1CA2CA7CA9 | |
| Cloflucarban SCHEMBL27537485 | 0.89 | KDR (0.88) | KDRCA1CA2CA7CA9 | |
| SCHEMBL16884950 | 0.88 | KDR (0.85) | KDRCA1CA2CA7CA9 | |
| SCHEMBL18615348 | 0.88 | KDR (0.85) | KDRCA1CA2CA7CA9 | |
| SCHEMBL281864 | 0.88 | KDR (0.85) | KDRCA1CA2CA7CA9 | |
| SCHEMBL4548158 | 0.88 | KDR (0.90) | KDRCA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015110-A2 | Anticoccidial composition, carbanilides and method of preparing them | ELI LILLY AND COMPANY (US) | 1980-09-03 | — | — | EP | claimed |
| EP-0015110-B1 | ANTICOCCIDIAL COMPOSITION, CARBANILIDES AND METHOD OF PREPARING THEM | ELI LILLY AND COMPANY (US) | 1985-08-21 | — | — | EP | disclosed |
| US-4526997-A | Amino, nitro, fluoro substituted carbanilides | DOHERTY GEORGE O P O | 1985-07-02 | — | — | US | disclosed |
| US-4468380-A | Anticoccidial combinations comprising polyether antibiotics and carbanilides | ELI LILLY AND COMPANY (US) | 1984-08-28 | — | — | US | disclosed |
| EP-0015110-A2 | Anticoccidial composition, carbanilides and method of preparing them | ELI LILLY AND COMPANY (US) | 1980-09-03 | — | — | EP | disclosed |