Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11005973 | 0.85 | CYP11B1 (0.44) | CYP19A1CYP11B1CYP11B2QPCTPTGS2 | |
| SCHEMBL11273678 | 0.82 | CYP17A1 (0.50) | CYP19A1CYP11B1CYP11B2POLBQPCT | |
| SCHEMBL11002369 | 0.82 | CYP19A1 (0.45) | CYP19A1CYP11B1CYP11B2POLB | |
| Hydrochloric Acid SCHEMBL10875164 | 0.81 | CYP17A1 (0.49) | CYP19A1CYP11B1CYP11B2POLBQPCT | |
| SCHEMBL8757551 | 0.81 | CYP19A1 (0.48) | CYP19A1CYP11B1CYP11B2POLBQPCT | |
| SCHEMBL28857747 | 0.79 | CYP19A1 (0.46) | CYP19A1CYP11B1CYP11B2POLBQPCT | |
| SCHEMBL11345480 | 0.79 | CYP19A1 (0.46) | CYP19A1CYP11B1CYP11B2POLBQPCT | |
| SCHEMBL10768224 | 0.78 | CYP11B1 (0.49) | CYP19A1CYP11B1CYP11B2PTGS2 | |
| Hydrochloric Acid SCHEMBL11343036 | 0.78 | CYP19A1 (0.44) | CYP19A1CYP11B1CYP11B2POLBQPCT | |
| SCHEMBL11084800 | 0.76 | CYP11B1 (0.46) | CYP19A1CYP11B1CYP11B2POLBQPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150036-A1 | Azolyl-aryl-alkanole-derivatives, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-07-31 | — | — | EP | claimed |