Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.68 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11005799 | 1.00 | AR (0.68) | ARSRD5A2KCNH2 | |
| SCHEMBL5213364 | 0.92 | AR (0.64) | ARSRD5A2KCNH2 | |
| SCHEMBL5213351 | 0.92 | AR (0.64) | ARSRD5A2KCNH2 | |
| SCHEMBL6402703 | 0.91 | SRD5A2 (0.65) | ARSRD5A2KCNH2 | |
| SCHEMBL7624227 | 0.91 | AR (0.67) | ARSRD5A2KCNH2 | |
| SCHEMBL7623411 | 0.90 | AR (0.62) | ARSRD5A2 | |
| SCHEMBL10631413 | 0.90 | AR (0.62) | ARSRD5A2 | |
| SCHEMBL5218085 | 0.90 | AR (0.63) | ARSRD5A2KCNH2 | |
| SCHEMBL7082767 | 0.90 | AR (0.63) | ARSRD5A2KCNH2 | |
| SCHEMBL7080135 | 0.90 | AR (0.71) | ARSRD5A2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155096-A2 | 17 Beta-Substituted-4-aza-5-alpha-androstenones and their use as 5-alpha-reductase inhibitors | MERCK & CO. INC. (US) | 1985-09-18 | — | — | EP | claimed |