Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | IAPP | P10997 | 1/20 | 0.35 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11000101 | 0.81 | KDM4E (0.49) | KDM4EHTTPKMMCL1TDP1 | |
| Triclopyr SCHEMBL149659 | 0.80 | TDP1 (0.45) | KDM4EHTTPKMMCL1TDP1 | |
| Triclopyr SCHEMBL29350609 | 0.80 | TDP1 (0.45) | KDM4EHTTPKMMCL1TDP1 | |
| Triclopyr SCHEMBL37162 | 0.80 | TDP1 (0.45) | KDM4EHTTPKMMCL1TDP1 | |
| Triclopyr SCHEMBL28421277 | 0.80 | KDM4E (0.43) | KDM4EHTTPKMMCL1TDP1 | |
| Triclopyr SCHEMBL23633000 | 0.79 | KDM4E (0.45) | KDM4EHTTPKMMCL1TDP1 | |
| Triclopyr SCHEMBL29157738 | 0.79 | TDP1 (0.44) | KDM4EHTTPKMMCL1TDP1 | |
| Triclopyr SCHEMBL25394124 | 0.79 | TDP1 (0.44) | KDM4EHTTPKMMCL1TDP1 | |
| Triclopyr SCHEMBL28924114 | 0.79 | TDP1 (0.44) | KDM4EHTTPKMMCL1TDP1 | |
| Triclopyr SCHEMBL29225326 | 0.79 | TDP1 (0.44) | KDM4EHTTPKMMCL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4552586-A | Certain 2-pyridyloxyacetanilides and their use as herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-11-12 | — | — | US | disclosed |
| EP-0060423-B1 | 2-PYRIDYLOXYACETANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-04-11 | — | — | EP | disclosed |