Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 2/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10980416 | 1.00 | CA4 (0.67) | CA4CA1CA2 | |
| Bromide SCHEMBL10964885 | 1.00 | CA4 (0.67) | CA4CA1CA2 | |
| Bromide SCHEMBL27322572 | 1.00 | — | — | |
| Bromide SCHEMBL28578674 | 0.87 | CA4 (0.50) | CA4 | |
| Bromide SCHEMBL5541 | 0.82 | — | — | |
| Bromide SCHEMBL186513 | 0.82 | — | — | |
| Potassium Ion SCHEMBL31039834 | 0.82 | — | — | |
| Bromide SCHEMBL187607 | 0.82 | CA4 (1.00) | CA4 | |
| Bromide SCHEMBL10505750 | 0.82 | — | — | |
| Bromide SCHEMBL5249818 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4551419-A | HIGH PHOTSENSITIVITY AND CONTRAST BY INCLUDING A SULFUR COMPOUND AND A MERCAPTO-CONTAINING AZAINDENE STABILIZER | FUJI PHOTO FILM CO., LTD. (JP) | 1985-11-05 | — | — | US | disclosed |