Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.85 |
| ▸ | PGR | P06401 | 2/20 | 0.85 |
| ▸ | PPARG | P37231 | 2/20 | 0.73 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.73 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.73 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.73 |
| ▸ | DAO | P14920 | 1/20 | 0.73 |
| ▸ | SNCA | P37840 | 1/20 | 0.73 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.73 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.72 |
| ▸ | HTR2C | P28335 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | ALB | P02768 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.64 |
| ▸ | APEX1 | P27695 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11009955 | 1.00 | NR1I2 (0.85) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11463469 | 0.95 | NR1I2 (0.86) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11463468 | 0.95 | NR1I2 (0.86) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11011238 | 0.95 | NR1I2 (0.81) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11011234 | 0.95 | NR1I2 (0.81) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Hydrochloric Acid SCHEMBL11481373 | 0.95 | NR1I2 (0.85) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Hydrochloric Acid SCHEMBL11481370 | 0.95 | NR1I2 (0.85) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10998892 | 0.94 | NR1I2 (0.85) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10998882 | 0.94 | NR1I2 (0.85) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL9659784 | 0.93 | NR1I2 (0.82) | NR1I2PGRPPARGSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4493833-A | BACTERICIDES, ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-01-15 | — | — | US | disclosed |
| US-4304770-A | Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-08 | — | — | US | disclosed |