Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.76 |
| ▸ | MAPT | P10636 | 5/20 | 0.76 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.76 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.76 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.76 |
| ▸ | ALB | P02768 | 1/20 | 0.76 |
| ▸ | PPARG | P37231 | 1/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.65 |
| ▸ | APEX1 | P27695 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10606264 | 0.93 | TDP1 (0.72) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10606259 | 0.93 | TDP1 (0.72) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11048288 | 0.92 | TDP1 (0.77) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11048282 | 0.92 | TDP1 (0.77) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11375976 | 0.92 | MAPT (0.65) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11246339 | 0.92 | MAPT (0.65) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10676259 | 0.91 | NR1I2 (0.67) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11372310 | 0.91 | MAPT (0.65) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11252200 | 0.91 | MAPT (0.64) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11247093 | 0.89 | NR1I2 (0.62) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282220-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-08-04 | — | — | US | claimed |
| US-4544751-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-10-01 | — | — | US | disclosed |
| EP-0017238-B1 | CEPHALOSPORIN DERIVATIVES AND PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-03-16 | — | — | EP | disclosed |
| US-4350693-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-09-21 | — | — | US | disclosed |
| EP-0006146-B1 | CEPHEM DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-09-15 | — | — | EP | disclosed |
| US-4282220-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-08-04 | — | — | US | disclosed |
| US-4263291-A | CEPHALOSPORIN ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-04-21 | — | — | US | disclosed |
| EP-0017238-A1 | Cephalosporin derivatives and process for their preparation and pharmaceutical compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-10-15 | — | — | EP | disclosed |
| EP-0006146-A1 | Cephem derivatives, process for their preparation and pharmaceutical compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-09 | — | — | EP | disclosed |